Morning Session
(9:00 AM - 1:00 PM)

9:00 - 9:30: Welcome and General Information.

• A. Cation cotransport: a historical perspective from discovery to cloning
  • 9:30 NKCCs from Geck to Soria (John Russell, Syracuse University, USA)
  • 10:00 K-Cl Cotransport from 1980 to present (Peter Lauf, Wright State University, USA)
• B. 10:30 From cloning to structure and function of chloride transporters (Gerardo Gamba, National University of Mexico, Mexico)
  
  11:00 - 12:00 WELCOME CEREMONY AND COFFEE BREAK
  
  
• C. 12:00 Ion selectivity and thermodynamics of chloride transporters (John Payne, University of California, Davis, USA)
• D. 12:00 CLC chloride channels: From cloning to structure and function (Thomas Jentsch, Hamburg University, Germany)

1:00 - 3:00  LUNCH BREAK


3:00 - 4:30  POSTERS

Afternoon Session
(4:30 PM - 7:00 PM)

• E. 4:30 Molecular Physiology of a New Family of Cl Channel, Bestrophins (Criss Hartzell, Emory University, USA)

• A. 5:00 Determination of intracellular chloride concentration with fluorescence lifetime imaging (Hiroshi Kaneko, University of Heidelberg, Germany)
  
  5:30 - 6:00 COFFEE BREAK
  
  
• B. 6:00 Chloride signaling in neurons imaged in transgenic mice expressing Clomeleon (George Augustine, Duke University, USA)
• C. 6:30 Estimating transmembrane chloride transport in neurons (Kevin Staley, University of Colorado, USA)

Morning Session
(8:30 AM - 1:00 PM)

• A. 8:30 Regulation of NKCC1 by cell volume (Else K. Hoffmann, University of Copenhagen, Denmark)
• B. 9:00 Water permeability of NKCC Cotransporters (Thomas Zeuthen, University of Copenhagen, Denmark)
• C. 9:30 Structure, function and regulation of the secretory Na-K-Cl cotransporter NKCC1 (Ignacio Giménez, University of Zaragoza, Spain)
• D. 10:00 Biology of gastrointestinal cation-chloride cotransporters (Chris Lytle, University of California, Riverside, USA)
  
  10:30 - 11:00 COFFEE BREAK
  
  
• E. 11:00 Thiazide-sensitive NaCl transporters (Gerardo Gamba, National University of Mexico, Mexico)
• F. 11:30 KCC structure function and regulation (David Mount, Harvard University, USA)
• G. 12:00 Regulation of cation chloride cotransporters by kinases (Eric Delpire, Vanderbilt University, USA)
• H. 12:30 Molecular physiology of SLC26 anion transporters (David Mount, Harvard University, USA and Michael Romero, Case Western Reserve University, USA)
  
  1:00 - 3:00  LUNCH BREAK
  
  
  3:00 - 4:30  FREE TIME
  
  

Afternoon Session
(4:30 PM - 8:00 PM)

• A. 4:30 Physiology and pathology of chloride channels (CLC) (Thomas Jentsch, Hamburg University, Germany)
• B. 5:00 Unveiling the role of purinergic receptors in the ATP-activated chloride conductance (Jorge Arreola, University of San Luis Potosí, México)
• C. 5:30 Chloride channels coupled to GABAc receptors in the brain. (Ataulfo Martinez Torres, Institute of Neurobiology, UNAM, Queretaro, Mexico)
  
  6:00 - 6:30 COFFEE BREAK
  
  

• A. 6:30 Role of GABA and of growth factors in the maturation of KCC2 function studied in culture (Ulrich Misgeld, University of Heidelberg, Germany)
• B. 7:00 Excitatory actions of GABA during development: the nature of nurture (Yehezkel Ben-Ari, University of Marseille, France)
• C. 7:30 Role of glycine, GABA, and chloride in auditory brainstem development (Eckhard Friauf, Kaiserslautern Technical University, Germany)

Morning Session
(9:00 AM - 1:00 PM)

• A. 9:00 Intracellular chloride homeostasis in nervous system function and dysfunction (F. Javier Alvarez-Leefmans, Wright State University, USA)
• B. 9:30 Gating properties of Ca2+-activated chloride channels (Stephan Frings, University of Heidelberg, Germany)
• C. 10:00 Mechanisms of the excitatory Cl^- response in mouse olfactory neurons (Jonathan Bradley, John Hopkins University, USA)
  
  10:30 - 11:00 COFFEE BREAK
  
  
• D. 11:00 Role of cation chloride cotransporters in cutaneous inflammation and pain. (William D. Willis, University of Texas, Galveston, USA)
• E. 11:30 Role of cation chloride cotransporters in joint inflammation and hyperalgesia (Karin Westlund-High, University of Texas, Galveston, USA)
• F. 12:00 Secondary hyperalgesia and presynaptic inhibition: role of cation-chloride cotransporters (Fernando Cervero, McGill University, Canada)
• G. 12:30 Neuronal chloride regulation and spontaneous network events in the immature hippocampus (Kai Kaila, University of Helsinki, Finland)
  
  1:00 - 3:00  LUNCH BREAK
  
  
  3:00 - 4:30  FREE TIME
  
  
  
  
  Afternoon Session
  (4:30 PM - 7:30 PM)
  
  

• H. 4:30 Cation-chloride cotransporters and GABAergic innervation in the human epileptic hippocampus (Alberto Muñoz, Cajal Institute, Spain and and F. Javier Alvarez-Leefmans, Wright state University, USA)
• I. 5:00 Intracellular chloride homeostasis in nervous system function and dysfunction (Guy Rouleau, McGill University, Canada)
  
  5:30 - 6:00 COFFEE BREAK
  
  

• A. 6:30 Interactions between chloride and bicarbonate transporters in cerebrospinal fluid secretion by the choroid plexus (Peter Brown, University of Manchester, UK)
• B 7:00 Na-K-Cl cotransporter and Na+/Ca2+ exchange in astrocyte mitochondrial dysfunction in response to in vitro ischemia (Dandan Sun, University of Wisconsin, USA)

Morning Session
(9:00 AM- 12:00 PM)

• A. 9:00 Cl- channels, apoptosis and the course Pseudomonas aeruginosa infection (Florian Lang, University of Tubingen, Germany)
• B. 9:30 Cytomegalovirus cell growth and NKCC (John Russell, Syracuse University, USA)
• C. 10:00 KCl Cotransport in cell growth, invasion and cancer (Clive Ellory, Oxford University, UK)
• D. 10:30 Role of cation chloride cotransporters in hypertension and kidney disease (Esteban Poch, University of Barcelona, Spain)
  
  11:30 - 12:00 CLOSING REMARKS